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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NFATC3
All Species:
23.33
Human Site:
Y605
Identified Species:
57.04
UniProt:
Q12968
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q12968
NP_004546.1
1075
115594
Y605
E
L
P
H
I
E
K
Y
S
I
N
S
C
S
V
Chimpanzee
Pan troglodytes
XP_001167633
1075
115585
Y605
E
L
P
H
I
E
K
Y
S
I
N
S
C
S
V
Rhesus Macaque
Macaca mulatta
XP_001088166
812
87865
R365
F
S
S
F
Q
H
I
R
K
G
G
F
C
D
Q
Dog
Lupus familis
XP_536809
1075
115741
Y605
E
L
P
H
I
E
K
Y
S
I
N
S
C
S
V
Cat
Felis silvestris
Mouse
Mus musculus
P97305
1075
115432
Y605
E
L
P
H
I
E
K
Y
S
I
N
S
C
S
V
Rat
Rattus norvegicus
NP_001101917
1068
115235
Y606
E
L
P
H
I
E
K
Y
S
I
N
S
C
S
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505280
629
67466
E183
G
R
P
Q
W
E
V
E
G
K
I
I
R
E
K
Chicken
Gallus gallus
XP_414078
1211
130585
Y727
E
L
P
Q
I
E
K
Y
S
I
N
S
C
S
V
Frog
Xenopus laevis
NP_001082217
884
97675
S438
A
V
K
A
V
T
G
S
H
P
I
V
K
L
I
Zebra Danio
Brachydanio rerio
XP_690273
1074
115220
A615
E
L
P
Q
V
E
K
A
S
I
S
S
C
P
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
37.2
93.4
N.A.
90.4
87
N.A.
42.7
66.6
52.5
60.1
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.7
47.9
96.1
N.A.
93.2
90.8
N.A.
46.7
74.9
64.3
70.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
6.6
100
N.A.
100
100
N.A.
13.3
93.3
0
66.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
6.6
100
N.A.
100
100
N.A.
13.3
93.3
20
80
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
10
0
0
0
10
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
80
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% D
% Glu:
70
0
0
0
0
80
0
10
0
0
0
0
0
10
0
% E
% Phe:
10
0
0
10
0
0
0
0
0
0
0
10
0
0
0
% F
% Gly:
10
0
0
0
0
0
10
0
10
10
10
0
0
0
0
% G
% His:
0
0
0
50
0
10
0
0
10
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
60
0
10
0
0
70
20
10
0
0
10
% I
% Lys:
0
0
10
0
0
0
70
0
10
10
0
0
10
0
10
% K
% Leu:
0
70
0
0
0
0
0
0
0
0
0
0
0
10
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
60
0
0
0
0
% N
% Pro:
0
0
80
0
0
0
0
0
0
10
0
0
0
10
0
% P
% Gln:
0
0
0
30
10
0
0
0
0
0
0
0
0
0
10
% Q
% Arg:
0
10
0
0
0
0
0
10
0
0
0
0
10
0
0
% R
% Ser:
0
10
10
0
0
0
0
10
70
0
10
70
0
60
0
% S
% Thr:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% T
% Val:
0
10
0
0
20
0
10
0
0
0
0
10
0
0
70
% V
% Trp:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
60
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _